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VOL. 8, ISSUE 1 (2026)
A cross sectional study on Evaluation of rapid diagnostic test for detection of hepatitis C at Integral Institute of Medical Sciences & Research, Lucknow
Authors
Khushboo Kumari, Dr. Noor Jahan
Abstract
Background: Rapid diagnostic test needs highly trained healthcare
worker, sample transport, provide fast TAT. The detection of HCV cannot be performed
independently they can be approved for use in India by the drug controller general
of India (DCGI). Hepatitis C is a positive sense ssRNA virus of family
flaviviridae consist of non-coding regions and genes encoding the core E1 and
E2. Aims- "To evaluate of Rapid Diagnostic Test for Detection of Hepatitis
C at Integral Institute of Medical Sciences & Research, Lucknow." This
study is a cross-sectional observational study conducted to evaluate the
performance of rapid diagnostic tests (RDTs) for the detection of Hepatitis C virus
(HCV) infection. The study was conducted in the Department of Microbiology, Integral
Institute of Medical Sciences and Research (IIMSR), Lucknow. Final sample size
is 80. Result - The results obtained in this study are consistent with findings
reported in previously published literature. As per Wen-Ge-Xing (2020), the sensitivity
of various HCV RDT kits ranged between 94% and 100%, while specificity varied
from 96% to 100%. In our study, the RDT demonstrated high concordance with
reference tests, suggesting strong potential for its use in clinical screening.
The high Negative Predictive Value (NPV) further reinforces the RDT’s utility
in ruling out HCV infection in asymptomatic individual. Conclusion- The study
concludes that RDTs can play a significant role in the early identification and
management of HCV infections, thereby contributing to broader public health efforts
aimed at controlling and eventually eliminating hepatitis C. However, further
multi-centric studies with larger sample sizes are recommended to reinforce the
findings and assess the generalizability and long-term impact of RDT-based
screening strategies.
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Pages:101-103
How to cite this article:
Khushboo Kumari, Dr. Noor Jahan "A cross sectional study on Evaluation of rapid diagnostic test for detection of hepatitis C at Integral Institute of Medical Sciences & Research, Lucknow". International Journal of Biotechnology and Microbiology, Vol 8, Issue 1, 2026, Pages 101-103
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