ARCHIVES
VOL. 7, ISSUE 4 (2025)
Implications of proteins and possibilities of vaccine molecule development for Epstein-Barr Virus (EBV) induced oral carcinomas
Authors
Hritik Chaudhary, Vinod Joshi, Bennet Angel, Annette Angel
Abstract
Oral cancer is one of the most widespread form
of cancer worldwide. It can be caused by various factors including smoking, alcohol
consumption and some viral infections. One of the most prevalent viral
infection causing oral carcinoma is associated with Epstein-Barr virus (EBV).
The aim of this review is to explore the techniques of identification
and analysis of different EBV-associated viral factors which can act as
antigens and aid in the development of effective immuno-therapies and to
explore various possibilities for the development of effective vaccine
molecule. After thorough review of published literature various EBV-associated
factors have been identified including Latent membrane proteins (LMPs),
EBV-associated nuclear antigens (EBNAs), long non-coding RNAs(lncRNAs) and
microRNAs, which aid in the viral progression and can be targeted for the
development of effective immuno-therapies. And different methods of vaccine
molecule development including nanoparticle vaccine, liposome-nanoparticle
vaccine and liposome adjuvant conjugated vaccine are also explored. This will
further add in our understanding of novel strategies for effective vaccine
development which might lead to the global eradication of EBV-associated
illnesses.
Download
Pages:81-86
How to cite this article:
Hritik Chaudhary, Vinod Joshi, Bennet Angel, Annette Angel "Implications of proteins and possibilities of vaccine molecule development for Epstein-Barr Virus (EBV) induced oral carcinomas". International Journal of Biotechnology and Microbiology, Vol 7, Issue 4, 2025, Pages 81-86
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.