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International Journal of
Biotechnology and Microbiology
ARCHIVES
VOL. 7, ISSUE 2 (2025)
The gut-brain interaction and the effect of bacteria on neurological disorders and the central nervous system- A review
Authors
Dr. Anuja Vajpayee, Pallavi Rai
Abstract
The microbiota-gut-brain connection is an intricate intercommunication system that connects our central nervous system to the gut. Recent research has thrown light on how important gut microbiota is for neurodevelopment, cognitive abilities, behavior, and even the underlying mechanisms of neurological and psychiatric disorders. Upon the microbial dysbalance in our gut, a condition known as gut dysbiosis arises, leading to various problems like Alzheimer’s and Parkinson’s diseases, autism spectrum disorders, anxiety, and depression. Even with the progress we’ve made, research in this field still faces hurdles, such as the variability of individual microbiomes, a lack of clear, abrupt evidence in humans, and unpredictability in research methods. However, there’s growing interest in promising treatments like probiotics, prebiotics, dietary changes, and fecal microbiota transplantation that could potentially influence brain function through the gut microbiome. Looking ahead, future studies that incorporate personalized medicine, metagenomics strategies, and large-scale human trials will play important roles in restoring the microbiota-gut-brain connection in order to cure mental and neurological health.
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Pages:31-37
How to cite this article:
Dr. Anuja Vajpayee, Pallavi Rai "The gut-brain interaction and the effect of bacteria on neurological disorders and the central nervous system- A review". International Journal of Biotechnology and Microbiology, Vol 7, Issue 2, 2025, Pages 31-37
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