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VOL. 6, ISSUE 4 (2024)
Antibacterial activity of four traditional medicinal plants from Western Ghats, India and identification of most active extract by GC-MS analysis
Authors
Prince Paul, Kabilan Muralidharan, Veeramuthu Duraipandiyan
Abstract
Infectious diseases caused by microbes lead to
the increase in the death toll every year. Bacterial strain undergoes
chromosomal mutation and thereby achieve antibiotic resistant which stands out
to be an important reason for the current health problems. Medicinal plants
inhibit the growth of microbes and helps in achieving better health. In the
present study, in vitro antibacterial activity was conducted for the 4
medicinal plants Alpinia galanga (L.) Willd, Blumea lacera,
Curcuma aeruginosa Roxb, and Pentanema indicum collected from
the western ghats against 10 pathogens. The activity was carried out for
the different extracts of all 4 plants. Pentanema indicum recorded highest
activity by inhibiting the growth of tested microbes at a concentration of
5mg/disc, against Vibrio cholerae with 17mm, Staphylococcus aureus – 15mm,
Pseudomonas fluorescens – 13mm, Klebsiella pneumoniae – 13mm, followed
by the chloroform extract of Pentanema indicum against Vibrio
cholerae with 15mm, Staphylococcus aureus – 14mm, Klebsiella
pneumoniae – 13mm. Alpinia galanga (Ethyl acetate) gave a
result against Pseudomonas fluorescens – 15mm, Bacillus aureus – 14mm,
Bacillus subtilis – 13mm. Hence, from the results, it can be concluded
that the ethyl acetate extract of P. indicum is a potent antibacterial
agent.
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Pages:24-29
How to cite this article:
Prince Paul, Kabilan Muralidharan, Veeramuthu Duraipandiyan "Antibacterial activity of four traditional medicinal plants from Western Ghats, India and identification of most active extract by GC-MS analysis". International Journal of Biotechnology and Microbiology, Vol 6, Issue 4, 2024, Pages 24-29
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