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VOL. 6, ISSUE 3 (2024)
Shampoo production as an antimicrobial agent from avocado (persea americana) pawpaw (carica papaya) and neem seeds (azadirachta indica) extract against dandruff causing organism (malassezia furfur)
Authors
Ebu Bridget, Funmilayo Ijebor, Kirfi S B, Saʹadatu Abdullahi
Abstract
Dandruff is a very common contagious hair problem that affects people
irrespective of age. The aim of this work is to produce shampoo as
antimicrobial agent from avocado, pawpaw and neem seeds against dandruff
causing organism (Malassezia furfur). Samples of avocado, pawpaw and
neem seed were collected within Bauchi metropolis and the test organism was
isolated using serial dilution while identification was based on cultural,
morphological and biochemical screening. Extract from the samples was obtained
using soxhlet extractor with n-hexane. The phytochemical screening of the
extract carried out revealed the presence of Alkaloids, Saponins, Glycosides
and Steroids in pawpaw and Neem seed while Glycoside was absent in avocado
extracts. The Minimum Inhibitory Concentration (MIC) carried out using agar
well diffusion method showed that the shampoo produced inhibits the test
organism (Malassezia furfur) with the highest zones of inhibitions at
12mm in 100% mg/ml and the lowest is at 7mm in 25%mg/ml while the commercial
shampoo (control) has the highest zone of inhibition at 20mm in 100% and the
lowest at 13mm in 25%mg/ml. The shampoo has the pH of 6.78. The foam value (mm)
was 350, and the solid content (%) was 22.1. The patch test for sensitivity
testing was also carried out and it shows no evidence of skin irritation and
allergic reaction. In conclusion herbal shampoo formulated with avocado, pawpaw
and neem seed was effective against Malasszie furfur. Thus, it can be
used in the treatment of dandruff.
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Pages:15-19
How to cite this article:
Ebu Bridget, Funmilayo Ijebor, Kirfi S B, Saʹadatu Abdullahi "Shampoo production as an antimicrobial agent from avocado (<i>persea americana</i>) pawpaw (<i>carica papaya</i>) and neem seeds (<i>azadirachta indica</i>) extract against dandruff causing organism (<i>malassezia furfur</i>)". International Journal of Biotechnology and Microbiology, Vol 6, Issue 3, 2024, Pages 15-19
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