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VOL. 6, ISSUE 2 (2024)
Phytochemicals Activity of Bacopa monnieri (L.) pennel.- A brief review
Authors
Priyanka Dubey, Ravi Upadhyaya, Anil Prakash
Abstract
This review brings out research with phytochemicals associated with
low-toxic cognitive enhancing actions of Bacopa monnieri, a medicinal
Ayurvedic herb. Bacopa monnieri is traditionally used for a variety of
ailments, but is best known as a nerve tonic and memory enhancer. Several
animal and in vitro studies have been conducted, which have found
evidence of several potential medicinal properties. Several randomized,
double-blind, placebo-controlled trials have confirmed Bacopa monnieri
nootropic utility in humans. There is also evidence of possible attenuation of
dementia, Parkinson's disease, and epilepsy. Current evidence suggests that Bacopa
monnieri acts through the following mechanisms—anti-oxidant neuroprotection
(via redox and enzyme induction), acetylcholinesterase inhibition and/or
choline acetyltransferase activation, β-amyloid reduction, in cerebral blood
flow growth, and neurotransmitter modulation (acetylcholine [ACh],
5-hydroxytryptamine [5-HT], dopamine [DA]). Bacopa monnieri appears to
exhibit low toxicity in model organisms and humans; However, long-term studies
of toxicity in humans have not yet been conducted. This review will integrate
phytochemicals in neuroscience with behavioral research.
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Pages:5-8
How to cite this article:
Priyanka Dubey, Ravi Upadhyaya, Anil Prakash "Phytochemicals Activity of <i>Bacopa monnieri</i> (L.) pennel.- A brief review". International Journal of Biotechnology and Microbiology, Vol 6, Issue 2, 2024, Pages 5-8
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