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International Journal of
Biotechnology and Microbiology
ARCHIVES
VOL. 5, ISSUE 4 (2023)
Effect of copper oxide nanoparticles as an Anti-bacterial in inhibiting the growth of E.coli
Authors
Ohood Salman Jawad, Rawaa T Alasadi, Hassanain Jwad Abidalhussein
Abstract
The present study focuses on investigating the inhibitory efficacy of copper oxide nanoparticles against the bacterial strain Escherichia coli, with the aim of evaluating their potential as antibacterial agents. Additionally, the research aims to determine the optimal concentration of zinc oxide nanoparticles required to effectively suppress the growth of E. coli. The study demonstrated the efficacy of zinc nanoparticles in inhibiting the growth of E. coli colonies cultivated on Petri plates. The concentrations and percentages evaluated in this investigation were 10%, 25%, 50%, 75%, and 100%, respectively. The minimal concentration of zinc oxide nanoparticles that is deemed effective as an antibacterial agent in suppressing the growth of E. coli bacteria is 50%. At this concentration, it is evident that the bacteria will not proliferate within a specific region on the plate. The inhibitory capacity exhibits an upward trend as the concentration of zinc nanoparticles escalates until it attains a level of 100%, which is deemed the optimal concentration, this concentration is juxtaposed with the antibiotic (cefotaxime), known for its efficacy in suppressing the proliferation of E. coli bacteria. The work demonstrates that the magnitude of the retarding area is 20 millimeters. Hence, based on the findings of this study, copper oxide nanoparticles can be regarded as a viable antimicrobial agent, demonstrating efficacy in combating various infections and diseases caused by E. coli. This efficacy is comparable to that of the antibiotic cefotaxime (CX30) in terms of inhibitory activity. The observed outcome and inhibitory efficacy in suppressing the proliferation of this particular strain of bacteria were identical.
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Pages:34-37
How to cite this article:
Ohood Salman Jawad, Rawaa T Alasadi, Hassanain Jwad Abidalhussein "Effect of copper oxide nanoparticles as an Anti-bacterial in inhibiting the growth of <i>E</i>.<i>coli</i>". International Journal of Biotechnology and Microbiology, Vol 5, Issue 4, 2023, Pages 34-37
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