Coronary
Atherosclerosis has a complicated etiology that is affected by risk factors
such as hereditary and environmental variables. Chronic infection and
inflammation have been identified as pathogenic factors for developing Coronary
Artery Disease (CA). This study aimed to identify the bacterial species that
could contribute to the occurrence of atherosclerosis in patients who underwent
cardiac catheterization of the coronary arteries in the period from 11/28/2022
to 4/15/2023 from the Mosul Center for Cardiology. and Cardiac Surgery (MCCCS).
Balloon
samples were transferred by Tryptone Soy Broth transport medium directly to the
laboratory, inoculated on primary isolation media (nutrient agar, blood agar,
and MacConkey agar), and incubated at 37 °C for 24 hours in aerobic condition.
This study showed that from 100 balloon samples isolating different species of
bacteria, 21 positive samples were obtained, and They represented 15 types,
according to the Vitek-2 compact system diagnosis. Isolating mixed types of
bacteria from atherosclerotic patients is an essential step in understanding
the potential role of bacterial infections in atherosclerosis, and can
investigate whether these bacteria promote inflammation, interact with lipids,
or trigger immune responses, all of which could play a role in the development
and progression of atherosclerosis. In conclusion, it was found that many types
of bacteria can be isolated from atherosclerosis, and it is believed that the
different isolated species are associated with different risk factors that
differ according to the patient, immunity, genetic predisposition, and other
environmental conditions surrounding him.
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