This study aims to evaluate the influence of regional honey. Aside from discovering an infection with honey at a cost lower than the price of antibiotics, and extracting a herbal alternative from honey to battle bacteria in addition to reducing the use of different antibiotics for patients, Robinia pseudoacacia on antibiotic-resistant Pseudomonas aeruginosa bacteria may be inhibited with honey without resorting to antibiotics. Investigate the genetic properties of bacteria. In previous studies, antibiotics such as imipenem-cilastatin-relebactam, a combination of carbapenem and relebactam, a beta-lactamase inhibitor that inhibits class A carbapenemases and class C cephalosporinases, in addition to aloe vera, were used to inhibit bacteria. Undiluted A. vera gel has been shown to affect all MDR isolates.